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Obviously this will be hypothetical based on logic/theory of how the immune system works

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates[J]

Furthermore, the changes in tryptophan fluorescence and the secondary structure of the proteins were found to be concomitant with respect to GdnHCl concentration

Pestic Biochem Phys 79:4957 Kostaropoulos I, Papadopoulos AI, Metaxakis A, Boukouvala E, Papadopoulou-Mourkidou E (2001) Glutathione S-transferase in the defence against pyrethroids in insects